| Servamp | July 5, 2016 | — | — |
| Servant × Service | July 5, 2013 | — | 13 |
| Seton Academy: Join the Pack! | January 7, 2020 | — | — |
| Seton Dōbutsuki | October 14, 1989 | — | 45 |
| Seven Mortal Sins | April 14, 2017 | — | 12 |
| Seven of Seven | January 10, 2002 | TV Tokyo | 25 |
| Seven Senses of the Re'Union | July 6, 2018 | — | 12 |
| Sexy Commando Gaiden | January 5, 1998 | TBS Television | — |
| Sgt. Frog | April 3, 2004 | TV Tokyo | 358 |
| Sgt. Frog☆ | October 3, 2026 | — | — |
| Shabake | October 3, 2025 | — | 13 |
| Shachibato! President, It's Time for Battle! | April 5, 2020 | — | 12 |
| Shadow Skill | October 25, 1995 | — | 4 |
| Shadow Skill: Eigi | July 3, 1998 | — | — |
| Shadow Star | July 7, 2003 | — | 13 |
| Shadows House | April 11, 2021 | — | 25 |
| Shadowverse | April 7, 2020 | — | — |
| Shakugan no Shana | October 6, 2005 | — | 72 |
| Shakugan no Shana S | October 23, 2009 | — | — |
| Shaman King | July 4, 2001 | TV Tokyo | 64 |
| Shaman King | April 1, 2021 | — | 52 |
| Shaman King: Flowers | January 10, 2024 | TX Network | 13 |
| Shamanic Princess | June 25, 1996 | — | — |
| Shangri-La | April 6, 2009 | Chiba Television Broadcasting | 24 |
| Shangri-La Frontier | October 1, 2023 | — | 50 |
| Shattered Angels | January 5, 2007 | — | 12 |
| She and Her Cat: Everything Flows | March 4, 2016 | — | 4 |
| She Professed Herself Pupil of the Wise Man | January 12, 2022 | — | 12 |
| Sherlock Hound | November 6, 1984 | TV Asahi | 26 |
| Shiba Inu Rooms | 2027 | — | — |
| Shiba Inuko-san | April 1, 2012 | — | 26 |
| Shibawanko no Wa no Kokoro | April 5, 2006 | NHK General TV | 80 |
| Shigofumi: Letters from the Departed | January 6, 2008 | — | 12 |
| Shigurui | July 19, 2007 | Toku | 12 |
| Shiki | July 8, 2010 | Fuji Television | 22 |
| Shikimori's Not Just a Cutie | April 10, 2022 | — | 12 |
| Shikizakura | October 10, 2021 | Chūkyō Television Broadcasting | — |
| Shima Shima Tora no Shimajirō | December 13, 1993 | TV Setouchi | 726 |
| Shimajirō Hesoka | April 5, 2010 | TV Setouchi | 202 |
| Shimajirō no Wow! | April 2, 2012 | TV Setouchi | — |
| Shimoneta | July 4, 2015 | — | 12 |
| Shin Ace o Nerae! | October 14, 1978 | — | 25 |
| Shin Atashin'chi | October 6, 2015 | — | 26 |
| Shin Bikkuriman | April 19, 1989 | — | 72 |
| Shin Getter Robo vs Neo Getter Robo | December 21, 2000 | — | 4 |
| Shin Hakkenden | April 3, 1999 | TV Aichi | 26 |
| Shin Ikki Tousen | May 17, 2022 | — | 3 |
| Shin KochiKame: Tokyo Beat Cops | 2027 | Fuji Television | — |
| Shin Maple Town Monogatari: Palm Town-hen | — | — | — |
| Shin Oishinbo | — | — | — |
| Shin-Men | November 26, 2010 | — | — |
| Shine On! Bakumatsu Boys | July 8, 2022 | — | — |
| Shine Post | July 13, 2022 | — | 12 |
| Shingu: Secret of the Stellar Wars | May 8, 2001 | NHK Satellite 2 Television | — |
| Shining Hearts: Shiawase no Pan | April 13, 2012 | — | 12 |
| Shining Tears X Wind | April 6, 2007 | — | 13 |
| Shinkai Densetsu Meremanoid | October 1, 1997 | — | 24 |
| Shinkalion Change the World | April 7, 2024 | — | — |
| Shinkansen Henkei Robo Shinkalion | January 6, 2018 | — | — |
| Shinkyoku Sōkai Polyphonica | April 3, 2007 | — | 12 |