| Tsuritama | April 13, 2012 | Fuji Television | — |
| Tsurune | October 22, 2018 | — | 26 |
| Tsurupika Hagemaru-kun | March 3, 1988 | — | 59 |
| Tsuyokiss | July 1, 2006 | — | 12 |
| Tune In to the Midnight Heart | January 6, 2026 | Kansai Telecasting Corporation | 12 |
| Turkey! Time to Strike | July 9, 2025 | — | 12 |
| Turn A Gundam | April 9, 1999 | — | 50 |
| Tweeny Witches | April 9, 2004 | NHK Educational TV | 40 |
| Tweeny Witches: The Adventures | — | — | 6 |
| Twilight Out of Focus | July 4, 2024 | — | 12 |
| Twin Angel Break | April 7, 2017 | — | 12 |
| Twin Angel: Twinkle Paradise | July 5, 2011 | — | 12 |
| Twin Princess of Wonder Planet | April 2, 2005 | TV Tokyo | 51 |
| Twin Signal: Family Game | September 21, 1996 | — | 3 |
| Twin Spica | November 1, 2003 | NHK Satellite 2 Television | 20 |
| Twin Star Exorcists | April 6, 2016 | — | — |
| Two Car | October 7, 2017 | — | 12 |
| Tying the Knot with an Amagami Sister | October 2, 2024 | — | 24 |
| Tytania | October 9, 2008 | NHK Satellite 2 Television | 26 |
| Tōhai | October 5, 2024 | — | 25 |
| Tōhō Niji Sōsaku Dōjin Anime: Musō Kakyō | — | — | — |
| Tōshō Daimos | April 1, 1978 | TV Asahi | 44 |
| Uchi no Maid ga Uzasugiru! | October 5, 2018 | AT-X | 12 |
| Uchi no Sanshimai | April 4, 2008 | TV Tokyo | 141 |
| Uchitama?! Have you seen my Tama? | January 10, 2020 | — | — |
| Uchurei! | — | — | — |
| Uchū Majin Daikengo | July 27, 1978 | — | — |
| Uchū Nanchara Kotetsu-kun | April 7, 2021 | NHK Educational TV | — |
| Uchūsen Sagittarius | January 10, 1986 | TV Asahi | 77 |
| UFO Baby | March 28, 2000 | NHK Satellite 2 Television | 78 |
| UFO Ultramaiden Valkyrie | July 4, 2002 | — | 24 |
| UFO Ultramaiden Valkyrie 3: Bride of Celestial Souls' Day | — | — | 6 |
| UFO Ultramaiden Valkyrie 4: Banquet of Time, Dreams, and Galaxies | July 21, 2006 | — | 2 |
| UFO Warrior Dai Apolon | April 6, 1976 | TBS Television | 47 |
| Uglymug, Epicfighter | July 6, 2025 | — | 12 |
| Ukkari Pénélope | November 20, 2006 | NHK Educational TV | 52 |
| Ultimate Girls | January 10, 2005 | — | 12 |
| Ultimate Otaku Teacher | April 4, 2015 | Yomiuri Telecasting Corporation | 24 |
| Ultra B | April 4, 1987 | — | 118 |
| Ultra Maniac | May 20, 2003 | — | 26 |
| Ultraman | April 1, 2019 | — | — |
| Ultraviolet: Code 044 | July 1, 2008 | — | — |
| Ulysses 31 | October 10, 1981 | France 3 | 26 |
| Ulysses: Jeanne d'Arc and the Alchemist Knight | October 7, 2018 | — | 12 |
| Umamusume: Cinderella Gray | April 6, 2025 | — | — |
| Umamusume: Pretty Derby | April 2, 2018 | — | — |
| Umayon | July 7, 2020 | — | 12 |
| Umayuru: Full Gate! | September 27, 2026 | — | — |
| Umeboshi Denka | April 1, 1969 | TBS Television | 26 |
| Umi Monogatari | June 24, 2009 | — | 12 |
| Umi no Minwa no Machi | December 2023 | — | 25 |
| Umineko When They Cry | July 2, 2009 | Chiba Television Broadcasting | 26 |
| Un-Go | October 13, 2011 | — | 11 |
| Unbreakable Machine-Doll | October 7, 2013 | — | 12 |
| Unbreakable Machine-Doll | December 25, 2013 | — | 6 |
| Uncle From Another World | July 6, 2022 | — | — |
| Uncle's Obsession with Cute Things | October 4, 2026 | — | — |
| Undead Girl Murder Farce | July 6, 2023 | — | 13 |
| Undead Unluck | October 7, 2023 | — | 24 |
| Undefeated Bahamut Chronicle | January 11, 2016 | — | 12 |