| Robotan | October 1, 1966 | — | 104 |
| Robotan | January 6, 1986 | — | 33 |
| Rosario + Vampire | January 3, 2008 | — | 26 |
| Rune Soldier | April 3, 2001 | WOWOW | 24 |
| RuriDragon | — | — | — |
| Sabagebu! | July 6, 2014 | — | 12 |
| Sailor Moon | March 7, 1992 | TV Asahi | 200 |
| Sakamoto Days | January 11, 2025 | — | 22 |
| Sakigake!! Otokojuku | February 25, 1988 | Fuji Television | 34 |
| Sakura Trick | January 9, 2014 | TBS Television | 12 |
| Sally the Witch | — | — | — |
| Samurai Pizza Cats | February 1, 1990 | — | 54 |
| Sarutobi Ecchan | October 4, 1971 | — | 26 |
| Sasaki and Miyano | January 10, 2022 | — | 12 |
| Sasuga no Sarutobi | October 17, 1982 | — | 69 |
| Sayonara, Zetsubou-Sensei | July 7, 2007 | — | — |
| School Babysitters | January 7, 2018 | — | 12 |
| Seitokai Yakuindomo | July 4, 2010 | — | 26 |
| Seitokai Yakuindomo | April 15, 2011 | — | 8 |
| Seitokai Yakuindomo * | May 16, 2014 | — | 8 |
| Seiyu's Life! | July 7, 2015 | — | 13 |
| Senyu | January 9, 2013 | — | 26 |
| Servant × Service | July 5, 2013 | — | 13 |
| Seven of Seven | January 10, 2002 | TV Tokyo | 25 |
| Sexy Commando Gaiden | January 5, 1998 | TBS Television | — |
| Shaman King | July 4, 2001 | TV Tokyo | 64 |
| Shaman King | April 1, 2021 | — | 52 |
| Shiba Inu Rooms | 2027 | — | — |
| Shiba Inuko-san | April 1, 2012 | — | 26 |
| Shimoneta | July 4, 2015 | — | 12 |
| Shin Atashin'chi | October 6, 2015 | — | 26 |
| Shinya! Tensai Bakabon | July 10, 2018 | TV Tokyo | 12 |
| Shō 3 Ashibe QQ Goma-chan | April 12, 2026 | TV Tokyo | — |
| Shōwa Ahō Zhoshi Akanuke Ichiban! | October 7, 1985 | — | 22 |
| Sket Dance | April 7, 2011 | TV Tokyo | 77 |
| Skull-face Bookseller Honda-san | October 8, 2018 | — | 12 |
| Slam Dunk | October 16, 1993 | TV Asahi | 101 |
| Slayers | April 7, 1995 | — | 104 |
| Slayers Excellent | October 25, 1998 | — | 3 |
| Slayers Special | July 25, 1996 | — | 3 |
| Sleepy Princess in the Demon Castle | October 6, 2020 | AT-X, TV Tokyo, BS TV Tokyo | 12 |
| Snack Basue | January 13, 2024 | — | 13 |
| Soar High! Isami | April 8, 1995 | NHK Educational TV | 50 |
| Sobakasu Pucchi | March 31, 1969 | Fuji Television | — |
| Softenni | April 8, 2011 | Tokyo MX | 12 |
| Sorcerer Hunters | October 3, 1995 | TV Tokyo | 26 |
| Sorcerer Hunters OVA | December 21, 1996 | — | 3 |
| Sorcerous Stabber Orphen | October 3, 1998 | TBS Television | 47 |
| Sorcerous Stabber Orphen | January 7, 2020 | — | 48 |
| Space Battleship Tiramisu | April 3, 2018 | — | 26 |
| Space Dandy | January 4, 2014 | — | 26 |
| Space Patrol Luluco | April 1, 2016 | Tokyo MX, AT-X, Nippon BS Broadcasting | 13 |
| Sparrow's Hotel | April 9, 2013 | — | 12 |
| Squid Girl | October 5, 2010 | TV Tokyo | 24 |
| Steins;Gate | April 6, 2011 | — | 26 |
| Stitch! | October 8, 2008 | — | 88 |
| Straight Title Robot Anime | February 6, 2013 | — | — |
| Strange+ | January 9, 2014 | — | 24 |
| Strawberry 100% | April 5, 2005 | TV Asahi | 12 |
| Strawberry Marshmallow | July 14, 2005 | — | 12 |