| Sky Wizards Academy | July 8, 2015 | — | 12 |
| Slayers | April 7, 1995 | — | 104 |
| Slayers Excellent | October 25, 1998 | — | 3 |
| Slayers Special | July 25, 1996 | — | 3 |
| Sleepy Princess in the Demon Castle | October 6, 2020 | AT-X, TV Tokyo, BS TV Tokyo | 12 |
| Snow White with the Red Hair | July 6, 2015 | — | 24 |
| So I'm a Spider, So What? | January 8, 2021 | — | 24 |
| So What's Wrong with Getting Reborn as a Goblin? | October 5, 2026 | — | — |
| Soara and the House of Monsters | 2027 | — | — |
| Sola | April 7, 2007 | — | 13 |
| Solo Leveling | January 7, 2024 | — | 25 |
| Somali and the Forest Spirit | January 9, 2020 | — | 12 |
| Sonic X | April 6, 2003 | TV Tokyo | 78 |
| Sora o Miageru Shōjo no Hitomi ni Utsuru Sekai | January 14, 2009 | — | 9 |
| Sorcerer Hunters | October 3, 1995 | TV Tokyo | 26 |
| Sorcerer Hunters OVA | December 21, 1996 | — | 3 |
| Sorcerous Stabber Orphen | October 3, 1998 | TBS Television | 47 |
| Sorcerous Stabber Orphen | January 7, 2020 | — | 48 |
| Soul Eater | April 7, 2008 | Toku | 51 |
| Soul Link | April 11, 2006 | — | 12 |
| Speed Grapher | April 7, 2005 | TV Asahi | 24 |
| Spice and Wolf | January 2008 | — | 26 |
| Spice and Wolf: Merchant Meets the Wise Wolf | April 2, 2024 | — | 25 |
| Spirit Circle | — | — | — |
| Steel Jeeg | October 5, 1975 | TV Asahi | 46 |
| Strait Jacket | — | — | — |
| Strange Dawn | July 11, 2000 | WOWOW | 13 |
| Strike the Blood | October 4, 2013 | — | 24 |
| Sugar Apple Fairy Tale | January 6, 2023 | — | 24 |
| Sugarbunnies | April 3, 2007 | — | 27 |
| Sugarbunnies: Chocolat! | April 9, 2008 | — | 27 |
| Sugarbunnies: Fleur | April 7, 2009 | — | 26 |
| Sunday Without God | July 6, 2013 | — | 12 |
| Superbook | October 9, 1981 | Christian Broadcasting Network | 52 |
| Suppose a Kid From the Last Dungeon Boonies Moved to a Starter Town | January 4, 2021 | — | 12 |
| Sweet Reincarnation | July 4, 2023 | — | 12 |
| Sword Oratoria: Is It Wrong to Try to Pick Up Girls in a Dungeon? On the Side | April 14, 2017 | — | 12 |
| Symphogear | January 6, 2012 | — | 65 |
| Taboo Tattoo | July 4, 2016 | — | 12 |
| Tales of Wedding Rings | January 6, 2024 | — | 12 |
| Tamagotchi! | October 12, 2009 | — | 143 |
| Tanken Driland | July 7, 2012 | — | — |
| Tanken Driland: Sennen no Mahō | April 6, 2013 | — | — |
| Tatakau Shisho | October 2, 2009 | — | — |
| Tayutama: Kiss on my Deity | April 5, 2009 | — | 12 |
| Tearmoon Empire | October 8, 2023 | — | 12 |
| Tears to Tiara | April 6, 2009 | — | 26 |
| Tegami Bachi | October 3, 2009 | TV Tokyo | — |
| Telepathy Shōjo Ran | June 21, 2008 | NHK Educational TV | 26 |
| Tenchi Muyo! Ryo-Ohki | — | — | 24 |
| Tenchi Muyo! War on Geminar | March 20, 2009 | — | 13 |
| Tenchi Universe | April 2, 1995 | — | 26 |
| Teogonia | April 12, 2025 | — | 12 |
| That Time I Got Reincarnated as a Slime | October 2, 2018 | — | 72 |
| The 8th Son? Are You Kidding Me? | April 2, 2020 | — | 12 |
| The Adventures of the Little Prince | July 4, 1978 | TV Asahi | 39 |
| The Asterisk War | October 3, 2015 | — | 24 |
| The Banished Court Magician Aims to Become the Strongest | October 4, 2025 | — | 12 |
| The Banished Former Hero Lives as He Pleases | April 2, 2024 | — | 12 |
| The Brilliant Healer's New Life in the Shadows | April 3, 2025 | — | 12 |