| Shikizakura | October 10, 2021 | Chūkyō Television Broadcasting | — |
| Shin Hakkenden | April 3, 1999 | TV Aichi | 26 |
| Shinzo | February 5, 2000 | — | 32 |
| Silent Möbius | April 7, 1998 | TV Tokyo | 26 |
| Silkroad Kids Yuto | September 16, 2006 | NHK Satellite 2 Television | 26 |
| Sky Girls | July 5, 2007 | Chiba Television Broadcasting | 26 |
| Solty Rei | October 6, 2005 | TV Asahi | 24 |
| Sonic X | April 6, 2003 | TV Tokyo | 78 |
| Sonny Boy | July 15, 2021 | — | 12 |
| Sound of the Sky | January 4, 2010 | TV Tokyo | 12 |
| Space Ace | May 8, 1965 | Fuji Television | 52 |
| Space Battleship Tiramisu | April 3, 2018 | — | 26 |
| Space Battleship Yamato | October 6, 1974 | Yomiuri Telecasting Corporation | 26 |
| Space Battleship Yamato II | October 14, 1978 | Yomiuri Telecasting Corporation | 26 |
| Space Battleship Yamato III | October 11, 1980 | Yomiuri Telecasting Corporation | 25 |
| Space Boy Soran | May 4, 1965 | — | 96 |
| Space Carrier Blue Noah | October 13, 1979 | — | 24 |
| Space Cobra | October 7, 1982 | — | 31 |
| Space Dandy | January 4, 2014 | — | 26 |
| Space Patrol Luluco | April 1, 2016 | Tokyo MX, AT-X, Nippon BS Broadcasting | 13 |
| Space Pirate Captain Harlock | March 14, 1978 | TV Asahi | 42 |
| Space Pirate Mito | January 5, 1999 | — | — |
| Space Runaway Ideon | May 8, 1980 | — | 39 |
| Space Symphony Maetel | August 5, 2004 | — | 15 |
| Spriggan | June 18, 2022 | Netflix | 6 |
| Star Blazers 2199 | April 7, 2013 | MBS | — |
| Stardust Telepath | October 9, 2023 | — | 12 |
| Starship Girl Yamamoto Yohko | April 4, 1999 | TV Osaka | 26 |
| Starship Girl Yamamoto Yohko | March 6, 1996 | — | 3 |
| Starship Girl Yamamoto Yohko II | August 6, 1997 | — | 3 |
| Starship Operators | January 5, 2005 | TV Tokyo | 13 |
| Starzinger | April 2, 1978 | Fuji Television | — |
| Steel Angel Kurumi | October 5, 1999 | — | 24 |
| Steel Angel Kurumi Encore | January 7, 2000 | — | 4 |
| Steins;Gate | April 6, 2011 | — | 26 |
| Steins;Gate 0 | April 12, 2018 | — | 23 |
| Stitch! | October 8, 2008 | — | 88 |
| Straight Title Robot Anime | February 6, 2013 | — | — |
| Strain: Strategic Armored Infantry | November 2, 2006 | — | 13 |
| Stratos 4 | January 5, 2003 | — | — |
| Super HxEros | July 4, 2020 | — | 12 |
| Super Jetter | January 7, 1965 | — | 52 |
| Super Milk Chan | June 18, 1998 | — | — |
| Sword Art Online | July 7, 2012 | Tokyo MX | 96 |
| Sword Art Online Alternative Gun Gale Online | April 8, 2018 | — | 12 |
| Synduality: Noir | July 11, 2023 | — | 24 |
| Tactical Roar | January 8, 2006 | — | 13 |
| Takopi's Original Sin | June 28, 2025 | — | 6 |
| Tatakae! Osper | December 14, 1965 | Nippon Television | 53 |
| Tekkaman Blade | February 18, 1992 | — | — |
| Tekkaman: The Space Knight | July 2, 1975 | — | 26 |
| Tenchi Muyo! GXP | April 3, 2002 | — | 26 |
| Tenchi Muyo! Ryo-Ohki | — | — | 24 |
| Terra Formars | September 26, 2014 | — | 26 |
| Terra Formars: Bugs 2 Arc | August 19, 2014 | — | 2 |
| Terra Formars: Earth Arc | August 17, 2018 | — | 2 |
| Tetsujin 28-go | April 7, 2004 | — | 26 |
| Texhnolyze | April 17, 2003 | — | 22 |
| The Amazing 3 | June 6, 1965 | Fuji Television | 52 |
| The Big O | October 13, 1999 | — | 26 |