| C. H. Greenblatt | screenwriter, animator, television producer, television director, voice actor, storyboard artist, television actor, dub actor | 2 |
| Cantinflas | screenwriter, actor, writer, military personnel, comedian, musician, stage actor, voice actor | 1 |
| Carl Barks | writer, farmer, animator, painter, cartoonist, journalist, comics writer, story artist | 1 |
| Carl Macek | screenwriter, television producer, comics artist, casting director, voice actor, film director, film producer, television actor | 1 |
| Carlo Collodi | writer, translator, journalist, children's writer, novelist | 1 |
| Carol-Lynn Parente | television producer | 1 |
| Carrie Beck | television producer | 1 |
| Celia Rico Clavellino | screenwriter, film director, film producer | 1 |
| Charles Addams | screenwriter, writer, animator, illustrator, comics artist, graphic artist, caricaturist, draftsperson | 1 |
| Charles Grosvenor | animator, film director, director | 1 |
| Charles Huettner | — | 1 |
| Charles M. Schulz | screenwriter, writer, artist, illustrator, comics artist, journalist, postage stamp designer, comics writer | 2 |
| Charles Swenson | screenwriter, animator, television producer, painter, film director, sound designer, film producer | 1 |
| Chelsea Beyl | writer, television producer, editor, dancer | 1 |
| Cheri Steinkellner | — | 1 |
| Chester Gould | comics artist | 1 |
| Chiaki Morosawa | screenwriter, writer | 2 |
| Chris Garbutt | screenwriter, illustrator, cartoonist, storyboard artist, producer | 1 |
| Chris Gifford | screenwriter, television producer, voice actor | 1 |
| Chris Kratt | screenwriter, actor, biologist, documentary filmmaker, television director, voice actor, television actor | 1 |
| Chris Licht | television producer, showrunner | 1 |
| Chris Nee | screenwriter, television producer, film producer, film screenwriter | 3 |
| Chris Prynoski | animator, executive producer, film director | 2 |
| Chris Savino | screenwriter, actor, animator, television producer, comics artist, director, storyboard artist | 1 |
| Chris Viscardi | screenwriter, television producer | 1 |
| Chris Witaske | television actor, film actor | 1 |
| Chris Wyatt | screenwriter, actor, author, film producer | 1 |
| Christian Linke | composer | 1 |
| Christine Ferraro | screenwriter | 1 |
| Christophe Barrier | animator | 1 |
| Christophe Izard | television producer | 2 |
| Christopher McCulloch | screenwriter, actor, television producer, comics artist, animation director, voice actor, film director, dub actor | 1 |
| Christy Hui | television producer | 1 |
| Christy Karacas | screenwriter, animator, television producer, musician, television director, voice actor, film director | 1 |
| Christy Marx | screenwriter, writer, game designer, video game director, television writer | 1 |
| Chuck Austen | inker, comics writer, penciller, television writer | 1 |
| Chuck Jones | screenwriter, actor, animator, comics artist, animation director, film director, film producer, director | 1 |
| Chuck Norris | screenwriter, actor, writer, stunt performer, film producer, television actor, film actor, taekwondo athlete | 1 |
| Claire Bretécher | comics writer | 1 |
| Claudio Biern Boyd | screenwriter, businessperson, television producer, television director, film director, film producer | 1 |
| Clea DuVall | screenwriter, actor, film director, television actor, film actor | 1 |
| Clive Bradley | screenwriter | 1 |
| Colin Dann | writer, children's writer, novelist, young adult author | 1 |
| Colonel Moutarde | illustrator, comics artist | 1 |
| Cory Edwards | screenwriter, writer, animator, voice actor, film director, film producer | 1 |
| Craig Bartlett | actor, writer, animator, television producer, director, storyboard artist, film screenwriter | 2 |
| Craig Gerber | baseball player | 1 |
| Craig Gerber | screenwriter, television producer | 1 |
| Craig Kyle | screenwriter, writer, film producer, comics writer | 1 |
| Craig McCracken | screenwriter, animator, television producer, cartoonist, television director | 4 |
| Cruz Delgado | comics artist, cartoonist, film director, film producer, director, film screenwriter | 1 |
| Cullen Crawford | — | 1 |
| Curtis Jobling | writer, animator, author, illustrator | 1 |