| Shadowverse | April 7, 2020 | — | — |
| Shaggy & Scooby-Doo Get a Clue! | September 23, 2006 | The CW, Kids' WB | 26 |
| Shakespeare: The Animated Tales | November 9, 1992 | BBC Two, S4C | 12 |
| Shakugan no Shana | October 6, 2005 | — | 72 |
| Shakugan no Shana S | October 23, 2009 | — | — |
| Shaman King | July 4, 2001 | TV Tokyo | 64 |
| Shaman King | April 1, 2021 | — | 52 |
| Shaman King: Flowers | January 10, 2024 | TX Network | 13 |
| Shamanic Princess | June 25, 1996 | — | — |
| Shangri-La | April 6, 2009 | Chiba Television Broadcasting | 24 |
| Shangri-La Frontier | October 1, 2023 | — | 50 |
| Shanna's Show | June 20, 2004 | Playhouse Disney | 14 |
| Shaolin Wuzang | December 13, 2006 | France 3 | 26 |
| Shape Island | January 20, 2023 | Apple TV | — |
| Shaq’s Garage | — | — | 52 |
| Sharkdog | September 3, 2021 | Netflix | — |
| Sharky & George | 1990 | Canal+, Canal Famille | 52 |
| Shasha & Milo | — | EBS 1TV | — |
| Shattered Angels | January 5, 2007 | — | 12 |
| Shaun the Sheep | March 5, 2007 | BBC One, BBC Children's and Education | 188 |
| Shazzan | September 9, 1967 | CBS | 36 |
| She and Her Cat: Everything Flows | March 4, 2016 | — | 4 |
| She Professed Herself Pupil of the Wise Man | January 12, 2022 | — | 12 |
| She-Ra and the Princesses of Power | November 13, 2018 | Netflix | 52 |
| She-Ra: Princess of Power | September 9, 1985 | Broadcast syndication | 93 |
| Sheep in the Big City | November 17, 2000 | Cartoon Network | 26 |
| Shenmue: The Animation | February 6, 2022 | Cartoon Network | 13 |
| Sheriff Callie's Wild West | December 13, 2013 | Disney Channel | 45 |
| Sherlock Holmes in the 22nd Century | May 6, 1999 | Fox Kids | 26 |
| Sherlock Hound | November 6, 1984 | TV Asahi | 26 |
| Sherlock Yack | May 4, 2011 | TF1 | 52 |
| Sherwood | March 6, 2019 | YouTube Premium | 10 |
| SheZow | December 15, 2012 | Network 10 | 26 |
| Shiba Inu Rooms | 2027 | — | — |
| Shiba Inuko-san | April 1, 2012 | — | 26 |
| Shibawanko no Wa no Kokoro | April 5, 2006 | NHK General TV | 80 |
| Shigofumi: Letters from the Departed | January 6, 2008 | — | 12 |
| Shigurui | July 19, 2007 | Toku | 12 |
| Shiki | July 8, 2010 | Fuji Television | 22 |
| Shikimori's Not Just a Cutie | April 10, 2022 | — | 12 |
| Shikizakura | October 10, 2021 | Chūkyō Television Broadcasting | — |
| Shima Shima Tora no Shimajirō | December 13, 1993 | TV Setouchi | 726 |
| Shimajirō Hesoka | April 5, 2010 | TV Setouchi | 202 |
| Shimajirō no Wow! | April 2, 2012 | TV Setouchi | — |
| Shimmer and Shine | August 24, 2015 | Nickelodeon, Nick Jr. Channel, TV Cultura | 86 |
| Shimoneta | July 4, 2015 | — | 12 |
| Shin Ace o Nerae! | October 14, 1978 | — | 25 |
| Shin Atashin'chi | October 6, 2015 | — | 26 |
| Shin Bikkuriman | April 19, 1989 | — | 72 |
| Shin Getter Robo vs Neo Getter Robo | December 21, 2000 | — | 4 |
| Shin Hakkenden | April 3, 1999 | TV Aichi | 26 |
| Shin Ikki Tousen | May 17, 2022 | — | 3 |
| Shin KochiKame: Tokyo Beat Cops | 2027 | Fuji Television | — |
| Shin Maple Town Monogatari: Palm Town-hen | — | — | — |
| Shin Oishinbo | — | — | — |
| Shin-Men | November 26, 2010 | — | — |
| Shine On! Bakumatsu Boys | July 8, 2022 | — | — |
| Shine Post | July 13, 2022 | — | 12 |
| Shingu: Secret of the Stellar Wars | May 8, 2001 | NHK Satellite 2 Television | — |
| Shining Girls | — | — | — |