| Strait Jacket | — | — | — |
| Strange Dawn | July 11, 2000 | WOWOW | 13 |
| Strange Planet | August 9, 2023 | Apple TV | — |
| Strange+ | January 9, 2014 | — | 24 |
| Stranger Things: Tales from '85 | April 23, 2026 | Netflix | 18 |
| Stratos 4 | January 5, 2003 | — | — |
| Strawberry 100% | April 5, 2005 | TV Asahi | 12 |
| Strawberry Marshmallow | July 14, 2005 | — | 12 |
| Strawberry Marshmallow | February 23, 2007 | — | 3 |
| Strawberry Marshmallow Encore | January 23, 2009 | — | 2 |
| Strawberry Panic! | April 3, 2006 | — | 26 |
| Strawberry Shortcake | March 11, 2003 | CBS, Broadcast syndication | 22 |
| Strawberry Shortcake's Berry Bitty Adventures | October 10, 2010 | Hub Network | 65 |
| Strawberry Shortcake: Berry in the Big City | September 18, 2021 | Wildbrain Entertainment | 120 |
| Street Fighter | October 21, 1995 | USA Action Extreme Team | 26 |
| Street Fighter II V | April 10, 1995 | — | 29 |
| Street Football | November 24, 2005 | France 3 | 104 |
| Street Sharks | September 11, 1994 | Broadcast syndication | 40 |
| Stressed Eric | April 20, 1998 | BBC Two | 13 |
| Stretch Armstrong & The Flex Fighters | November 17, 2017 | Netflix | 13 |
| Strike the Blood | October 4, 2013 | — | 24 |
| Strike the Blood Final | March 30, 2022 | — | 4 |
| Strike the Blood II | — | — | 8 |
| Strike the Blood III | — | — | 10 |
| Strike the Blood IV | — | — | 12 |
| Strike the Blood: Valkyria no Ōkoku-hen | — | — | 2 |
| Strike Witches | July 3, 2008 | — | 12 |
| Strike Witches 2 | July 7, 2010 | — | 12 |
| Strike Witches: 501st Joint Fighter Wing Take Off! | April 9, 2019 | — | 12 |
| Strike Witches: Operation Victory Arrow | September 20, 2014 | — | 3 |
| Strike Witches: Road to Berlin | — | — | — |
| Strip Law | February 20, 2026 | — | — |
| Stripperella | June 26, 2003 | Spike TV, Paramount Network | 13 |
| Stroker and Hoop | August 1, 2004 | Adult Swim | 13 |
| Stuart Little | March 1, 2003 | HBO | 13 |
| Student Council's Discretion | October 2, 2009 | Nippon Television | 12 |
| Studio Apartment, Good Lighting, Angel Included | April 6, 2024 | — | 12 |
| Studio Cabana | 2027 | — | — |
| Stunt Dawgs | September 28, 1992 | — | 40 |
| Subete ga F ni Naru | October 8, 2015 | Fuji Television | 11 |
| Submarine Jim | January 11, 2026 | France 4, RTS 2, RTS 1, Cartoon Network, CBBC, Cartoon Network, La Trois, ABC Entertains | 52 |
| Submarine Super 99 | May 8, 2003 | AT-X | 13 |
| Sue Cat | April 6, 1980 | — | 40 |
| Sugar Apple Fairy Tale | January 6, 2023 | — | 24 |
| Sugar Soldier | January 14, 2014 | — | 3 |
| Sugar Sugar Rune | July 2, 2005 | TV Tokyo | 51 |
| Sugarbunnies | April 3, 2007 | — | 27 |
| Sugarbunnies: Chocolat! | April 9, 2008 | — | 27 |
| Sugarbunnies: Fleur | April 7, 2009 | — | 26 |
| Sugarland | — | — | — |
| Suicide Squad Isekai | June 27, 2024 | HBO Max | 10 |
| Suika | February 25, 2003 | — | 4 |
| Suikoden | October 3, 2026 | — | — |
| Suite PreCure | February 6, 2011 | TV Asahi | 48 |
| Sukeban Deka | — | — | — |
| Sukisho | January 7, 2005 | — | 13 |
| Summer Camp Island | July 7, 2018 | Cartoon Network, HBO Max | 120 |
| Summer Memories | — | — | — |
| Summer Pockets | April 7, 2025 | — | 26 |
| Summer Time Rendering | April 14, 2022 | — | 25 |