| Ensemble Stars! | July 7, 2019 | — | 24 |
| Epithet Erased | — | VRV | 7 |
| Erased | January 8, 2016 | — | 12 |
| Eren the Southpaw | April 8, 2026 | — | 13 |
| Ergo Proxy | February 25, 2006 | WOWOW, Fuse | 23 |
| Erin | January 10, 2009 | NHK General TV | 50 |
| Erky Perky | September 7, 2006 | Seven Network | 78 |
| Ernest & Rebecca | March 24, 2019 | TF1 | 52 |
| Ernest le Vampire | 1989 | France 3 | 117 |
| Eromanga Sensei | April 9, 2017 | — | 12 |
| Esme & Roy | August 18, 2018 | HBO, Treehouse TV, PBS Kids, HBO Max | 52 |
| Estab-Life: Great Escape | April 7, 2022 | Fuji Television | 12 |
| Esther's Notebooks | September 3, 2018 | Canal+ | — |
| Eternal Boys | October 11, 2022 | — | 24 |
| Ethelbert the Tiger | 2005 | CBeebies | 52 |
| Etotama | April 9, 2015 | — | 12 |
| Eunha’s Diary | — | MBC TV | — |
| Eureka Seven | April 17, 2005 | TBS Television | 50 |
| Eureka Seven: AO | April 12, 2012 | — | — |
| Eureka Seven: Hi-Evolution | — | — | — |
| Eureka! | June 22, 2022 | Disney Jr. | 30 |
| Even a Replica Can Fall in Love | April 7, 2026 | — | 13 |
| Even Given the Worthless "Appraiser" Class, I'm Actually the Strongest | January 9, 2025 | — | 12 |
| Even the Student Council Has Its Holes! | October 4, 2026 | — | — |
| Even Though I'm a Super Timid Noble Girl, I Accepted the Bet From My Cunning Fiancé | October 4, 2026 | — | — |
| Ever Night | — | — | — |
| Everybody Loves a Moose | — | — | — |
| Everybody Still Hates Chris | September 25, 2024 | Paramount+ | — |
| Everyday Host | April 5, 2025 | — | — |
| Everyone's Darling Has a Secret | April 2027 | — | — |
| Everything for Demon King Evelogia | October 1, 2021 | — | 9 |
| Evil Con Carne | July 11, 2003 | Cartoon Network | 14 |
| Evil or Live | October 10, 2017 | — | — |
| Ewilan's Quest | December 27, 2025 | RTS 1 | 8 |
| Ewoks | September 7, 1985 | American Broadcasting Company | 35 |
| Ex-Arm | January 11, 2021 | — | 12 |
| Excel Saga | October 8, 1999 | TV Tokyo | 26 |
| Exosquad | September 11, 1993 | Broadcast syndication | 52 |
| Explorer Woman Ray | May 26, 1989 | — | 2 |
| Extreme Dinosaurs | September 1, 1997 | Broadcast syndication | 52 |
| Extreme Ghostbusters | September 1, 1997 | Broadcast syndication | 40 |
| Extreme Hearts | July 10, 2022 | — | 12 |
| Eyes of Wakanda | August 1, 2025 | Disney+ | 4 |
| Eyeshield 21 | April 6, 2005 | TV Tokyo | 145 |
| F | March 9, 1988 | Fuji Television | 31 |
| F Is for Family | December 18, 2015 | Netflix | 44 |
| F-Zero: GP Legend | October 7, 2003 | TX Network | — |
| F3 | — | — | — |
| Fables of the Green Forest | January 7, 1973 | — | 52 |
| Fabre-sensei wa Meitantei | April 11, 2000 | NHK Satellite 2 Television | 26 |
| Fabulous Funnies | September 9, 1978 | NBC | 13 |
| Face on Lie | — | — | — |
| Fafner in the Azure | July 4, 2004 | — | 26 |
| Failure Frame | July 5, 2024 | — | 12 |
| Fairfax | October 29, 2021 | — | 16 |
| Fairies Albums | April 25, 2020 | — | 60 |
| Fairview | February 9, 2022 | Comedy Central | 8 |
| Fairy Gone | April 7, 2019 | — | 24 |
| Fairy Ranmaru | April 8, 2021 | — | 12 |
| Fairy Tail | October 12, 2009 | TV Tokyo | 328 |