| Deep Space 69 | July 15, 2012 | — | 40 |
| Deepa & Anoop | August 15, 2022 | Netflix | — |
| Deer Squad | July 15, 2020 | — | — |
| Defenders of the Earth | September 8, 1986 | Broadcast syndication | 65 |
| Dennis the Menace | September 22, 1986 | CBS, Broadcast syndication | 78 |
| Denver, the Last Dinosaur | September 12, 1988 | — | 50 |
| Deputy Dawg | September 8, 1962 | CBS | 34 |
| Descendants: Wicked World | September 18, 2015 | Disney Channel | 33 |
| Detention | September 11, 1999 | — | 13 |
| Devil May Care | February 6, 2021 | Syfy | 7 |
| Dexter's Laboratory | April 28, 1996 | Cartoon Network | 78 |
| Dexter: Early Cuts | 2009 | — | 24 |
| Diabolik | January 1, 2000 | Italia 1, Fox Kids | 40 |
| Dick and Paula Celebrity Special | 1999 | — | 7 |
| Dicktown | July 9, 2020 | FXX | — |
| Digman! | March 22, 2023 | Comedy Central | — |
| Dilbert | January 25, 1999 | UPN | 30 |
| Dink, the Little Dinosaur | September 16, 1989 | CBS | 21 |
| Dinky Dog | September 9, 1978 | CBS | 16 |
| Dino Boy in the Lost Valley | September 10, 1966 | CBS | 18 |
| Dino Girl Gauko | 2019 | — | — |
| Dino-Riders | October 1, 1988 | Broadcast syndication | 14 |
| Dinosaucers | September 14, 1987 | Broadcast syndication | 65 |
| Dinosaur Train | September 7, 2009 | PBS, PBS Kids | 100 |
| DinoSquad | November 3, 2007 | CBS, KidsCo, Cookie Jar TV | 26 |
| Dinotrux | August 14, 2015 | Netflix | 78 |
| Disenchantment | August 17, 2018 | Netflix | 50 |
| Disney's Adventures of the Gummi Bears | September 14, 1985 | NBC | 65 |
| Disney's House of Mouse | January 13, 2001 | American Broadcasting Company | 52 |
| Distant Lands | June 25, 2020 | Cinemax, HBO Max | 4 |
| Dive Olly Dive! | October 8, 2006 | KiKA, Seven Network, Qubo | 104 |
| DJ & the Fro | May 31, 2009 | MTV | 12 |
| Doc McStuffins | March 23, 2012 | Disney Jr. | 136 |
| Doctor Dolittle | September 12, 1970 | NBC | 17 |
| Dog City | September 26, 1992 | Fox Broadcasting Company | 31 |
| Dogs in Space | November 18, 2021 | Netflix | 20 |
| Domo-kun | October 2008 | Nickelodeon | 26 |
| Donald Duck Presents | September 1, 1983 | Disney Channel | — |
| Donald's Quack Attack | 1992 | — | — |
| DOOOD, What The?! | — | — | — |
| Dora | September 30, 2023 | — | — |
| Dora | April 12, 2024 | Paramount+ | 26 |
| Dora and Friends: Into the City! | August 18, 2014 | Nickelodeon | 28 |
| Dora the Explorer | August 14, 2000 | Nickelodeon | 172 |
| Dorothy and The Wizard of Oz | June 26, 2017 | Boomerang, Cartoon Network, Televiziunea Română, France 3 | 60 |
| Dot. | September 6, 2016 | CBC Television, Universal Kids | 78 |
| Dota: Dragon's Blood | March 25, 2021 | Netflix | 24 |
| Double Dragon | September 12, 1993 | Broadcast syndication | 26 |
| Doug | August 11, 1991 | Nickelodeon, American Broadcasting Company | 117 |
| Doug Unplugs | November 13, 2020 | Apple TV | — |
| Downtown | August 3, 1999 | MTV, MTV2 | 13 |
| Dr. Katz, Professional Therapist | May 28, 1995 | Comedy Central | 86 |
| Dragon Flyz | September 6, 1996 | France 3 | 26 |
| Dragon Tales | September 6, 1999 | PBS Kids, CBC Kids | 93 |
| Dragon's Lair | September 8, 1984 | American Broadcasting Company | 13 |
| Drak Pack | September 6, 1980 | CBS | 16 |
| Drawn Together | October 27, 2004 | Comedy Central | 36 |
| Dream Defenders | 2011 | — | 26 |
| Dream Productions | December 11, 2024 | Disney+ | 4 |
| DreamWorks Dragons | September 4, 2012 | Cartoon Network, Netflix | 118 |