| Salamander | — | — | — |
| Salaryman's Club | January 30, 2022 | — | 12 |
| Sally Bollywood: Super Detective | October 26, 2009 | Seven Network, France 3, Pop Girl, 7Two | 104 |
| Sally the Witch | — | — | — |
| Sally the Witch 2 | October 9, 1989 | — | — |
| Sammy & Co | July 20, 2014 | — | 107 |
| Samuel | 2024 | — | 21 |
| Samurai 7 | June 12, 2004 | NHK Digital Satellite HD | 26 |
| Samurai Champloo | May 19, 2004 | Fuji Television | 26 |
| Samurai Deeper Kyo | July 1, 2002 | — | 26 |
| Samurai Flamenco | October 10, 2013 | Fuji Television | 22 |
| Samurai Giants | October 7, 1973 | — | 48 |
| Samurai Girl: Real Bout High School | July 30, 2001 | Kids Station | 13 |
| Samurai Gun | October 5, 2004 | AT-X, TV Asahi | 13 |
| Samurai Harem: Asu no Yoichi | January 8, 2009 | — | 12 |
| Samurai Jack | August 10, 2001 | Adult Swim, Cartoon Network | 62 |
| Samurai Pizza Cats | February 1, 1990 | — | 54 |
| Samurai Rabbit: The Usagi Chronicles | April 28, 2022 | Netflix | — |
| Samurai Spirits 2: Asura Zanmaden | — | — | — |
| Samurai Warriors | January 12, 2015 | — | — |
| Samyy malenkiy gnom | 1977 | — | — |
| Sand Land: The Series | March 20, 2024 | — | — |
| Sanda | October 4, 2025 | — | 12 |
| Sandmännchen | November 22, 1959 | Deutscher Fernsehfunk | 22,200 |
| Sandra the Fairytale Detective | 2009 | Italia 1, TG4, Disney XD, Kidz/Animez, Qubo, Gloobinho | 52 |
| Sanjay and Craig | May 25, 2013 | Nickelodeon | 45 |
| Sankarea: Undying Love | April 5, 2012 | — | 12 |
| Sanrio Boys | January 6, 2018 | — | — |
| Santa Inc. | December 2, 2021 | HBO Max | — |
| Santiago of the Seas | October 9, 2020 | Nickelodeon | 58 |
| Santo Bugito | September 16, 1995 | CBS | 13 |
| Sanxingdui Glory Awakening | — | Kaku Children's Television | 52 |
| Sarah & Duck | February 18, 2013 | CBeebies | 160 |
| Sarazanmai | April 11, 2019 | — | 11 |
| Saredo Tsumibito wa Ryū to Odoru | April 5, 2018 | — | 12 |
| Saru Get You -On Air- | April 8, 2006 | TBS Television | — |
| Sarutobi Ecchan | October 4, 1971 | — | 26 |
| Sasaki and Miyano | January 10, 2022 | — | 12 |
| Sasaki and Peeps | January 5, 2024 | — | 12 |
| Sasami-san@Ganbaranai | January 11, 2013 | — | 12 |
| Sasami: Magical Girls Club | April 13, 2006 | — | 26 |
| Sasuga no Sarutobi | October 17, 1982 | — | 69 |
| Sasurai no Shōjo Nell | October 25, 1979 | TV Tokyo | 26 |
| Saturday Morning All Star Hits! | December 10, 2021 | — | — |
| Saturday Supercade | September 17, 1983 | CBS | 26 |
| SauceRia | — | KBS 2TV | 26 |
| Sauerkraut | December 6, 1992 | ZDF | 13 |
| Sausage Party: Foodtopia | July 11, 2024 | Amazon Prime Video | 16 |
| Saved by the Ice Cold Prince's Embrace | July 7, 2026 | — | 12 |
| Saving 80,000 Gold in Another World for My Retirement | January 8, 2023 | — | 12 |
| Say I Love You | October 6, 2012 | — | 13 |
| Sayed Android | June 6, 2016 | — | — |
| Sayonara, Zetsubou-Sensei | July 7, 2007 | — | — |
| Sazae-san | October 5, 1969 | Fuji Television | — |
| Scan2Go | August 9, 2010 | Seoul Broadcasting System | 52 |
| Scar on the Praeter | January 9, 2021 | — | 13 |
| Scared Rider Xechs | July 5, 2016 | — | 12 |
| Scaredy Squirrel | April 1, 2011 | YTV | 52 |
| Scarlet Nexus | July 1, 2021 | — | 26 |
| Scary Larry | — | — | 52 |