| The Rolling Girls | January 10, 2015 | — | 12 |
| The Roman Holidays | September 9, 1972 | NBC | 13 |
| The Rose of Versailles | October 10, 1979 | Nippon Television | 40 |
| The Rotten Fruit | — | — | — |
| The Royal Tutor | April 4, 2017 | — | 12 |
| The Ruff & Reddy Show | December 14, 1957 | NBC | 50 |
| The Ryuo's Work is Never Done! | January 8, 2018 | Tokyo MX | 12 |
| The Sacred Blacksmith | December 19, 2009 | AT-X | 12 |
| The Sado Life of Rosé the Witch | — | — | — |
| The Saga of Noggin the Nog | — | — | — |
| The Saga of Tanya the Evil | January 6, 2017 | — | 12 |
| The Saint's Magic Power Is Omnipotent | April 6, 2021 | — | 24 |
| The Samsonadzes | November 2009 | Imedi Media Holding | 18 |
| The Saurini | — | — | 104 |
| The Savage Dragon | September 21, 1995 | USA Network | 26 |
| The Scarlet Rose | February 9, 2026 | Canal+ Kids | 20 |
| The Scooby & Scrappy-Doo/Puppy Hour | September 25, 1982 | American Broadcasting Company | 13 |
| The Scooby-Doo Show | September 11, 1976 | American Broadcasting Company | 40 |
| The Scooby-Doo/Dynomutt Hour | September 11, 1976 | American Broadcasting Company | 16 |
| The Seal of Neptune | 1960 | — | 18 |
| The Second Best Hospital in the Galaxy | February 23, 2024 | Amazon Prime Video | — |
| The Secret Files of the Spy Dogs | 1998 | Fox Broadcasting Company | 22 |
| The Secret Forest of Wind | — | KBS 1TV | 12 |
| The Secret Railroad | January 13, 1979 | ICI Radio-Canada Télé | 52 |
| The Secret Saturdays | October 3, 2008 | Cartoon Network | 36 |
| The Secret Show | September 16, 2006 | CBBC, BBC Children's and Education | 52 |
| The Secret World of Benjamin Bear | September 15, 2003 | Family Channel | 52 |
| The Secret World of Santa Claus | December 1, 1997 | France 3 | 26 |
| The Sensibles | — | — | 12 |
| The Seven Deadly Sins | October 5, 2014 | — | 100 |
| The Seven Heavenly Virtues | January 26, 2018 | — | 10 |
| The Seven Knights of the Marronnier Kingdom | October 3, 2026 | NHK Educational TV | — |
| The Seven Wishes | March 1, 2025 | MBC 2 | — |
| The Severing Crime Edge | April 4, 2013 | — | 13 |
| The Shadoks | April 29, 1968 | Office de radiodiffusion télévision française | 208 |
| The Shadownsters | 2015 | — | — |
| The Share House's Secret Rule | January 5, 2025 | — | 8 |
| The Shiunji Family Children | April 8, 2025 | — | 12 |
| The Shivering Truth | — | Adult Swim | — |
| The Shnookums and Meat Funny Cartoon Show | January 2, 1995 | Broadcast syndication | 13 |
| The Shoe People | April 1987 | TV-am | 26 |
| The Shy Hero and the Assassin Princesses | July 5, 2025 | — | 12 |
| The Silent Service | December 18, 1995 | — | 3 |
| The Silver Brumby | October 29, 1994 | Network 10, Nine Network | 39 |
| The Silver Guardian | April 1, 2017 | — | — |
| The Simpsons | December 17, 1989 | Fox Broadcasting Company | 814 |
| The Sisters | August 28, 2017 | M6 | 156 |
| The Skull Dragon's Precious Daughter | 2027 | — | — |
| The Skull King | — | KBS 2TV | 8 |
| The Skull Man | April 28, 2007 | — | 13 |
| The Slime Diaries: That Time I Got Reincarnated as a Slime | April 6, 2021 | — | 12 |
| The Smoggies | September 2, 1989 | France 2, ICI Radio-Canada Télé | 52 |
| The Smokey Bear Show | September 6, 1969 | American Broadcasting Company | 17 |
| The Smurfs | September 12, 1981 | NBC | 256 |
| The Smurfs | November 12, 1961 | — | — |
| The Smurfs | April 18, 2021 | La Trois | 104 |
| The Snoopy Show | February 5, 2021 | Apple TV | — |
| The Snow Queen | May 22, 2005 | NHK General TV | 36 |
| The sofia's book | November 20, 2006 | Telecaribe | — |
| The Song of Tentomushi | October 6, 1974 | — | 104 |