| Metalocalypse | August 6, 2006 | Adult Swim, Cartoon Network | 63 |
| Mickey and the Roadster Racers | — | — | — |
| Mickey Mouse | June 28, 2013 | Disney Channel | 96 |
| Mickey Mouse and Friends | 1994 | — | — |
| Mickey Mouse Clubhouse | May 5, 2006 | Playhouse Disney, Disney Channel, Disney Jr. | 125 |
| Mickey Mouse Clubhouse+ | July 21, 2025 | Disney Jr. | 20 |
| Mickey Mouse Funhouse | August 20, 2021 | Disney Jr. | 85 |
| Mickey Mouse Mixed-Up Adventures | January 15, 2017 | Disney Jr. | 87 |
| Mickey Mouse Works | May 1, 1999 | American Broadcasting Company | 25 |
| Mickey's Mouse Tracks | November 2, 1992 | — | — |
| Middle School Moguls | September 2, 2019 | Nickelodeon | — |
| Middlemost Post | July 9, 2021 | Nickelodeon | 33 |
| Mighty Ducks | September 6, 1996 | American Broadcasting Company | 26 |
| Mighty Magiswords | September 29, 2016 | Cartoon Network | 92 |
| Mighty Man and Yukk | — | — | — |
| Mighty Max | September 12, 1993 | Broadcast syndication | 40 |
| Mighty Mouse: The New Adventures | September 19, 1987 | CBS | 19 |
| Mighty Orbots | — | — | — |
| Mike Judge Presents: Tales from the Tour Bus | September 22, 2017 | Cinemax | 16 |
| Mike Tyson Mysteries | October 27, 2014 | Adult Swim, Cartoon Network | 30 |
| Mike, Lu & Og | November 12, 1999 | Cartoon Network | 26 |
| Milo Murphy's Law | October 3, 2016 | Disney XD | 35 |
| Mina and the Count | November 5, 1995 | Nickelodeon, Cartoon Network | 6 |
| Minecraft | — | Netflix | — |
| Minecraft Mini-Series | — | — | — |
| Minnie's Bow-Toon's: Party Palace Pals | April 5, 2021 | Disney Jr. | — |
| Minnie's Bow-Toons | November 14, 2011 | Disney Channel, Disney Jr. | 40 |
| Minoriteam | March 19, 2006 | Adult Swim | 19 |
| Minuscule | October 18, 2006 | Disney Channel, France 2, MBC 2, JeemTV | 78 |
| Mira, Royal Detective | March 20, 2020 | Disney Jr. | 54 |
| Mission Force One | February 6, 2015 | Disney Channel, Disney Jr. | 12 |
| Mission Hill | September 24, 1999 | The WB | 13 |
| Mission: Magic! | September 8, 1973 | American Broadcasting Company | 16 |
| Mister T | September 17, 1983 | NBC | 30 |
| Mixels | February 12, 2014 | Cartoon Network | 31 |
| Moby Dick and Mighty Mightor | September 9, 1967 | CBS | 18 |
| Molly of Denali | July 15, 2019 | PBS, PBS Kids | 67 |
| Monchhichis | — | American Broadcasting Company | 13 |
| Mongo Wrestling Alliance | January 23, 2011 | Adult Swim, Cartoon Network | 10 |
| Monster Farm | 1998 | — | — |
| Monster High | May 5, 2010 | YouTube | 182 |
| Monster High | October 6, 2022 | Nickelodeon | 33 |
| Monster Mania | September 11, 1995 | Broadcast syndication, CITV | 26 |
| Monsters at Work | 2021 | Disney+ | 20 |
| Monsters vs. Aliens | March 23, 2013 | Nickelodeon | 26 |
| Monsuno | February 23, 2012 | Nicktoons | 65 |
| Moon Girl and Devil Dinosaur | February 10, 2023 | Disney Channel | 30 |
| Moonbeam City | September 16, 2015 | Comedy Central | 10 |
| Moral Orel | December 13, 2005 | Adult Swim | 43 |
| Mork & Mindy/Laverne & Shirley/Fonz Hour | September 25, 1982 | American Broadcasting Company | 27 |
| Mortal Kombat: Defenders of the Realm | September 21, 1996 | USA Network | 13 |
| Motel Transylvania | 2025 | Netflix | — |
| Mother Goose and Grimm | September 14, 1991 | CBS | 10 |
| Motorcity | April 30, 2012 | Disney XD | 20 |
| Motown Magic | November 20, 2018 | Netflix | 25 |
| Mouseterpiece Theater | April 18, 1983 | Disney Channel | 60 |
| Moville Mysteries | September 7, 2002 | Nickelodeon | 26 |
| Mr. Bogus | January 1, 1991 | Broadcast syndication | 58 |
| Mr. Pickles | September 21, 2014 | Adult Swim | 20 |
| Mr. Wong | 2000 | — | 15 |