| Little Wizards | September 26, 1987 | American Broadcasting Company | 13 |
| Littlest Pet Shop | October 16, 1995 | Broadcast syndication | 40 |
| Littlest Pet Shop | November 10, 2012 | TF1 | 104 |
| Littlest Pet Shop: A World of Our Own | April 14, 2018 | Discovery Family | 52 |
| Lloyd in Space | February 3, 2001 | American Broadcasting Company | 39 |
| Loafy | — | — | — |
| Long Live the Royals | May 16, 2014 | Cartoon Network | 4 |
| Long Story Short | August 22, 2025 | Netflix | 10 |
| Loonatics Unleashed | September 17, 2005 | The WB | 26 |
| Looney Tunes Cartoons | May 27, 2020 | HBO Max | 82 |
| Lost in Oz | June 26, 2015 | Amazon Prime Video | 26 |
| Lost Ollie | August 24, 2022 | Netflix | — |
| Love, Death & Robots | March 15, 2019 | Netflix | 26 |
| Lu & the Bally Bunch | March 17, 2023 | Cartoon Network, CBeebies, CBC Kids, RTÉ KIDSjr, HBO Max, Cartoonito, CBC Gem | 76 |
| Lucas Bros. Moving Co. | November 23, 2013 | Fox Broadcasting Company | 17 |
| Lucky Luke | 1983 | France Régions 3 | 26 |
| Lucy, the Daughter of the Devil | October 30, 2005 | Adult Swim, Cartoon Network | 11 |
| Lugar Heights | — | — | — |
| Luna Petunia: Return to Amazia | February 2, 2018 | Netflix | — |
| Lyla in the Loop | February 5, 2024 | PBS Kids | — |
| M.A.S.K. | September 16, 1985 | CBS, TF1 | 75 |
| M.O.D.O.K. | May 21, 2021 | Hulu | 10 |
| Mad | September 6, 2010 | Cartoon Network | 103 |
| Mad Jack the Pirate | September 12, 1998 | Fox Broadcasting Company, Fox Kids | 13 |
| Madagascar: A Little Wild | September 7, 2020 | Hulu, Peacock | 45 |
| Madeline | September 12, 1993 | Freeform, Treehouse TV, ICI Radio-Canada Télé, France 3 | 59 |
| Madness Combat | July 25, 2002 | — | — |
| Magical Girl Friendship Squad | September 26, 2020 | Syfy | — |
| Maisy | February 11, 1999 | CITV | 28 |
| Make Way for Noddy | September 2, 2002 | PBS, PBS Kids | 100 |
| Making Fiends | October 4, 2008 | Nicktoons | 6 |
| Mao Mao: Heroes of Pure Heart | July 1, 2019 | Cartoon Network | 40 |
| Marsupilami | September 18, 1993 | CBS | 29 |
| Martha Speaks | September 1, 2008 | PBS Kids, TVO Media Education Group | 96 |
| Marvel Anime | October 1, 2010 | Animax, G4 | 48 |
| Marvel Super Hero Adventures | October 13, 2017 | — | — |
| Marvel Zombies | September 24, 2025 | Disney+ | 4 |
| Marvel's Avengers Assemble | May 26, 2013 | Disney XD | 127 |
| Marvel's Spider-Man | August 19, 2017 | Disney XD | 58 |
| Mary Shelley's Frankenhole | June 27, 2010 | Adult Swim, Cartoon Network | 20 |
| Mary-Kate and Ashley in Action! | October 20, 2001 | American Broadcasting Company | 26 |
| Maryoku Yummy | October 11, 2010 | Discovery Family | 26 |
| Masters of the Universe: Revelation | July 23, 2021 | Netflix | 15 |
| Matty's Funday Funnies | October 11, 1959 | — | — |
| Max & the Midknights | October 30, 2024 | Nickelodeon | 10 |
| Max Steel | February 26, 2000 | Cartoon Network, The WB | 36 |
| Max Steel | March 25, 2013 | Disney XD | 54 |
| Max Steel Turbo Missions | — | — | — |
| Maxie's World | September 14, 1987 | Broadcast syndication | 32 |
| Maya & Miguel | October 11, 2004 | PBS, PBS Kids Go! | 65 |
| Maya and the Three | October 22, 2021 | Netflix | 9 |
| Me & Mickey | — | — | — |
| Meatballs & Spaghetti | September 18, 1982 | CBS | 21 |
| Mech Cadets | August 10, 2023 | Netflix | 10 |
| Meekah | 2022 | — | 66 |
| Mega Man | September 11, 1994 | Broadcast syndication | 27 |
| Mega Man: Fully Charged | August 5, 2018 | Cartoon Network, WildBrainTV | 26 |
| Megas XLR | 2002 | Cartoon Network | 26 |
| Men in Black: The Series | October 11, 1997 | CBS, The WB | 53 |
| Merrie Melodies Starring Bugs Bunny & Friends | September 17, 1990 | Broadcast syndication | 65 |