| Egyxos | February 22, 2015 | Super! | 26 |
| Ejen Ali | April 8, 2016 | TV3 | 15 |
| El Chapulín Colorado | April 13, 2015 | Channel 5 (Mexico) | 74 |
| El Chavo Animado | October 21, 2006 | Grupo Televisa, TLN Network, Univision, Cartoon Network, Galavisión, Sistema Brasileiro de Televisão, UniMás, Band, SIC K, Channel 5 (Mexico) | 139 |
| El Deafo | — | — | — |
| El Perro Chocolo | — | — | — |
| El Tigre: The Adventures of Manny Rivera | March 3, 2007 | Nickelodeon | 26 |
| El tonno | March 14, 2002 | ProSieben | 34 |
| Elena of Avalor | July 22, 2016 | Disney Channel | 25 |
| ELF Academy | — | — | — |
| Elinor Wonders Why | September 7, 2020 | PBS Kids | 40 |
| Eliot Kid | March 3, 2008 | CBBC, BBC Children's and Education | 52 |
| Ella Bella Bingo | — | NRK Super | — |
| Elliott from Earth | March 6, 2021 | Cartoon Network | 16 |
| Eloise: The Animated Series | October 10, 2006 | Starz | 13 |
| Emara | — | — | 5 |
| Emily | 1979 | Antenne 2 | 49 |
| Endangered Species | March 3, 2015 | Cartoon Network | 26 |
| Engie Benjy | September 4, 2002 | CITV | 52 |
| Epithet Erased | — | VRV | 7 |
| Erky Perky | September 7, 2006 | Seven Network | 78 |
| Ernest & Rebecca | March 24, 2019 | TF1 | 52 |
| Ernest le Vampire | 1989 | France 3 | 117 |
| Esme & Roy | August 18, 2018 | HBO, Treehouse TV, PBS Kids, HBO Max | 52 |
| Esther's Notebooks | September 3, 2018 | Canal+ | — |
| Ethelbert the Tiger | 2005 | CBeebies | 52 |
| Eunha’s Diary | — | MBC TV | — |
| Eureka! | June 22, 2022 | Disney Jr. | 30 |
| Everybody Loves a Moose | — | — | — |
| Everybody Still Hates Chris | September 25, 2024 | Paramount+ | — |
| Evil Con Carne | July 11, 2003 | Cartoon Network | 14 |
| Ewilan's Quest | December 27, 2025 | RTS 1 | 8 |
| Ewoks | September 7, 1985 | American Broadcasting Company | 35 |
| Exosquad | September 11, 1993 | Broadcast syndication | 52 |
| Extreme Dinosaurs | September 1, 1997 | Broadcast syndication | 52 |
| Extreme Ghostbusters | September 1, 1997 | Broadcast syndication | 40 |
| Eyes of Wakanda | August 1, 2025 | Disney+ | 4 |
| F Is for Family | December 18, 2015 | Netflix | 44 |
| Fabulous Funnies | September 9, 1978 | NBC | 13 |
| Face on Lie | — | — | — |
| Fairfax | October 29, 2021 | — | 16 |
| Fairies Albums | April 25, 2020 | — | 60 |
| Fairview | February 9, 2022 | Comedy Central | 8 |
| Fairy Tale Police Department | 2001 | — | 26 |
| Fairyteens | — | — | — |
| Familia Telerín | 1964 | RTVE | — |
| Family Dog | June 23, 1993 | CBS | 10 |
| Family Guy | January 31, 1999 | Fox Broadcasting Company | 461 |
| Family Story | April 6, 2015 | KBS 1TV | 150 |
| Family Whizz | — | Guangdong Television | 65 |
| Famous 5: On the Case | April 5, 2008 | France 3 | 43 |
| Fanboy & Chum Chum | November 6, 2009 | Nickelodeon | 52 |
| Fancy Nancy | July 13, 2018 | Disney Jr. | 63 |
| Fangbone! | March 29, 2016 | WildBrainTV | 52 |
| Fangface | September 9, 1978 | American Broadcasting Company | 32 |
| Fantadroms | 1985 | — | 13 |
| Fantaghirò | 1999 | Telecinco | 26 |
| Fantastic Four | September 24, 1994 | Broadcast syndication | 26 |
| Fantastic Four: World's Greatest Heroes | September 2, 2006 | Cartoon Network | 26 |
| Fantastic Max | September 11, 1988 | Broadcast syndication | 26 |