| Mikrobi | January 4, 1976 | — | 13 |
| Moby Dick and Mighty Mightor | September 9, 1967 | CBS | 18 |
| Murder Drones | 2021 | YouTube | — |
| My Life as a Teenage Robot | August 1, 2003 | Nickelodeon | 40 |
| Nanocore | — | — | — |
| New Captain Scarlet | February 12, 2005 | ITV | 26 |
| Nutri Ventures | September 26, 2012 | RTP2 | 102 |
| Once Upon a Time... Planet Earth | December 22, 2008 | France 3 | 26 |
| Once Upon a Time... Space | October 2, 1982 | France Régions 3 | 26 |
| Pantheon | September 1, 2022 | AMC+ | 16 |
| Penn Zero: Part-Time Hero | December 5, 2014 | Disney XD, Disney XD | 35 |
| Pet Alien | January 23, 2005 | Cartoon Network | 52 |
| Phantom 2040 | September 18, 1994 | Broadcast syndication | 35 |
| Phineas and Ferb | August 17, 2007 | Disney Channel, Disney XD | 255 |
| Pinky and the Brain | September 9, 1995 | The WB | 66 |
| Planet Sheen | October 2, 2010 | Nickelodeon | 26 |
| Power Players | September 21, 2019 | Cartoon Network | 78 |
| Quantum Heroes Dinoster | — | EBS 1TV, EBS America | 35 |
| Ready Jet Go! | February 15, 2016 | PBS Kids | 64 |
| Regular Show | September 6, 2010 | Cartoon Network | 261 |
| Return to the Planet of the Apes | September 6, 1975 | NBC | 13 |
| Rick and Morty | December 2, 2013 | Adult Swim | 71 |
| Rick and Morty: The Non-Canonical Adventures | — | — | 36 |
| Rise of the Teenage Mutant Ninja Turtles | July 20, 2018 | Nicktoons, Nickelodeon | 26 |
| Robotboy | November 1, 2005 | Cartoon Network, France 3 | 52 |
| Robotomy | October 25, 2010 | Cartoon Network | 10 |
| Robozuna | October 18, 2018 | ITV | 20 |
| Rocket Robin Hood | October 9, 1966 | — | 52 |
| Roughnecks: Starship Troopers Chronicles | August 30, 1999 | Broadcast syndication | 36 |
| Scavengers Reign | October 19, 2023 | HBO Max | 12 |
| Sealab 2020 | September 9, 1972 | NBC | 13 |
| Shadow Raiders | September 16, 1998 | YTV | 26 |
| Shazzan | September 9, 1967 | CBS | 36 |
| She-Ra and the Princesses of Power | November 13, 2018 | Netflix | 52 |
| She-Ra: Princess of Power | September 9, 1985 | Broadcast syndication | 93 |
| Sherlock Holmes in the 22nd Century | May 6, 1999 | Fox Kids | 26 |
| Sherwood | March 6, 2019 | YouTube Premium | 10 |
| Sidekick | September 3, 2010 | YTV | 52 |
| Silver Surfer | February 7, 1998 | Fox Broadcasting Company | 13 |
| SilverHawks | September 8, 1986 | Broadcast syndication | 65 |
| Skeleton Warriors | March 23, 1995 | CBS | 13 |
| Slugterra | September 3, 2012 | WildBrainTV | 50 |
| Solar Opposites | 2020 | Hulu | 63 |
| Sonic Prime | December 15, 2022 | Netflix | 23 |
| Sonic the Hedgehog | September 18, 1993 | American Broadcasting Company | 26 |
| Sonic Underground | September 9, 1998 | TF1 | 40 |
| Space Angel | — | — | — |
| Space Cats | September 14, 1991 | NBC | 13 |
| Space Chickens in Space | September 30, 2018 | Nine Network | 52 |
| Space Ghost | September 10, 1966 | CBS | 42 |
| Space Strikers | September 10, 1995 | M6 | 26 |
| Spaceballs: The Animated Series | June 4, 2008 | Super Channel | 13 |
| Speed Racer: The Next Generation | May 2, 2008 | Nicktoons | 52 |
| Spicy City | July 11, 1997 | HBO | 6 |
| Spider-Man | November 19, 1994 | Fox Broadcasting Company, Fox Kids | 65 |
| Spider-Man and His Amazing Friends | September 12, 1981 | NBC | 24 |
| Spider-Man: The New Animated Series | July 11, 2003 | MTV | 13 |
| Spider-Woman | September 22, 1979 | American Broadcasting Company | 16 |
| Spiral Zone | September 21, 1987 | Broadcast syndication | 65 |
| SpongeBob SquarePants | May 1, 1999 | Nickelodeon, ARB Günəş | 330 |