| The Plucky Duck Show | September 19, 1992 | Fox Broadcasting Company, Fox Kids | 13 |
| The Poddington Peas | — | — | — |
| The Porky Pig Show | September 20, 1964 | — | 26 |
| The Power Team | 1990 | USA Network | 55 |
| The Powerpuff Girls | November 18, 1998 | Cartoon Network | 78 |
| The Powerpuff Girls | April 4, 2016 | Cartoon Network | 119 |
| The Prince | — | Hulu | 12 |
| The Problem Solverz | April 4, 2011 | Cartoon Network | 26 |
| The Proud Family | September 15, 2001 | Disney Channel | 52 |
| The Proud Family: Louder and Prouder | February 23, 2022 | Disney+ | 29 |
| The Puppy's Further Adventures | September 25, 1982 | American Broadcasting Company | 21 |
| The Quick Draw McGraw Show | September 28, 1959 | Broadcast syndication | 35 |
| The Raccoons | 1980 | CBC Television | 60 |
| The Raggy Dolls | April 3, 1986 | ITV | 112 |
| The Ranch | — | TF1 | 52 |
| The Ravages of Time | — | Bilibili | — |
| The Real Adventures of Jonny Quest | August 26, 1996 | Cartoon Network | 52 |
| The Real Ghostbusters | September 13, 1986 | American Broadcasting Company | 140 |
| The Reluctant Dragon & Mr. Toad Show | September 12, 1970 | American Broadcasting Company | 17 |
| The Ren & Stimpy Show | August 11, 1991 | Nickelodeon | 52 |
| The Replacements | July 28, 2006 | Disney Channel, Toon Disney, ABC Kids | 52 |
| The Return of Dogtanian | — | La 1 | 26 |
| The Richie Rich/Scooby-Doo Show | November 8, 1980 | American Broadcasting Company | 21 |
| The Ricky Gervais Show | February 19, 2010 | HBO | 39 |
| The Ripping Friends | September 7, 2001 | Nickelodeon, Fox Kids, Treehouse TV, La 1, Cartoon Network | 13 |
| The Road Runner Show | September 10, 1966 | — | 48 |
| The Robonic Stooges | September 10, 1977 | CBS | 32 |
| The Rocketeer | November 8, 2019 | Disney Channel, Disney Jr. | 22 |
| The Rocky and Bullwinkle Show | November 19, 1959 | American Broadcasting Company | 163 |
| The Roman Holidays | September 9, 1972 | NBC | 13 |
| The Rotten Fruit | — | — | — |
| The Ruff & Reddy Show | December 14, 1957 | NBC | 50 |
| The Saga of Noggin the Nog | — | — | — |
| The Samsonadzes | November 2009 | Imedi Media Holding | 18 |
| The Saurini | — | — | 104 |
| The Savage Dragon | September 21, 1995 | USA Network | 26 |
| The Scarlet Rose | February 9, 2026 | Canal+ Kids | 20 |
| The Scooby & Scrappy-Doo/Puppy Hour | September 25, 1982 | American Broadcasting Company | 13 |
| The Scooby-Doo Show | September 11, 1976 | American Broadcasting Company | 40 |
| The Scooby-Doo/Dynomutt Hour | September 11, 1976 | American Broadcasting Company | 16 |
| The Seal of Neptune | 1960 | — | 18 |
| The Second Best Hospital in the Galaxy | February 23, 2024 | Amazon Prime Video | — |
| The Secret Files of the Spy Dogs | 1998 | Fox Broadcasting Company | 22 |
| The Secret Forest of Wind | — | KBS 1TV | 12 |
| The Secret Railroad | January 13, 1979 | ICI Radio-Canada Télé | 52 |
| The Secret Saturdays | October 3, 2008 | Cartoon Network | 36 |
| The Secret Show | September 16, 2006 | CBBC, BBC Children's and Education | 52 |
| The Secret World of Benjamin Bear | September 15, 2003 | Family Channel | 52 |
| The Secret World of Santa Claus | December 1, 1997 | France 3 | 26 |
| The Sensibles | — | — | 12 |
| The Seven Wishes | March 1, 2025 | MBC 2 | — |
| The Shadoks | April 29, 1968 | Office de radiodiffusion télévision française | 208 |
| The Shadownsters | 2015 | — | — |
| The Shivering Truth | — | Adult Swim | — |
| The Shnookums and Meat Funny Cartoon Show | January 2, 1995 | Broadcast syndication | 13 |
| The Shoe People | April 1987 | TV-am | 26 |
| The Silver Brumby | October 29, 1994 | Network 10, Nine Network | 39 |
| The Simpsons | December 17, 1989 | Fox Broadcasting Company | 814 |
| The Sisters | August 28, 2017 | M6 | 156 |
| The Skull King | — | KBS 2TV | 8 |