| Star Wars: The Bad Batch | May 4, 2021 | Disney+ | 18 |
| Star Wars: The Clone Wars | October 3, 2008 | Cartoon Network, Netflix, Disney+ | 133 |
| Star Wars: Visions | September 22, 2021 | Disney+ | 18 |
| Star Wars: Young Jedi Adventures | May 4, 2023 | Disney Channel | 19 |
| Starcom: The U.S. Space Force | September 20, 1987 | Broadcast syndication | 13 |
| Stargate Infinity | September 14, 2002 | Fox Broadcasting Company | 26 |
| Starship Regulars | — | — | 10 |
| Starveillance | January 5, 2007 | E! | 6 |
| Static Shock | September 23, 2000 | The WB | 52 |
| Steven Universe | November 4, 2013 | Cartoon Network | 108 |
| Steven Universe Future | December 7, 2019 | Cartoon Network | 20 |
| Stevie and Zoya | 1987 | — | — |
| Stillwater | December 4, 2020 | Apple TV | 40 |
| Stone Quackers | October 27, 2014 | — | 12 |
| Stories from my Childhood | 1998 | — | — |
| Storm Hawks | May 25, 2007 | Cartoon Network, YTV | 52 |
| Strange Planet | August 9, 2023 | Apple TV | — |
| Stranger Things: Tales from '85 | April 23, 2026 | Netflix | 18 |
| Strawberry Shortcake | March 11, 2003 | CBS, Broadcast syndication | 22 |
| Strawberry Shortcake's Berry Bitty Adventures | October 10, 2010 | Hub Network | 65 |
| Strawberry Shortcake: Berry in the Big City | September 18, 2021 | Wildbrain Entertainment | 120 |
| Street Fighter | October 21, 1995 | USA Action Extreme Team | 26 |
| Street Sharks | September 11, 1994 | Broadcast syndication | 40 |
| Stressed Eric | April 20, 1998 | BBC Two | 13 |
| Stretch Armstrong & The Flex Fighters | November 17, 2017 | Netflix | 13 |
| Stripperella | June 26, 2003 | Spike TV, Paramount Network | 13 |
| Stroker and Hoop | August 1, 2004 | Adult Swim | 13 |
| Stuart Little | March 1, 2003 | HBO | 13 |
| Stunt Dawgs | September 28, 1992 | — | 40 |
| Summer Camp Island | July 7, 2018 | Cartoon Network, HBO Max | 120 |
| Sunny Day: Style of Girls | July 2026 | Nick Jr. | 1 |
| Super Best Friends Forever | March 17, 2012 | Cartoon Network | 5 |
| Super Chicken | — | — | — |
| Super Dave: Daredevil for Hire | September 12, 1992 | Fox Broadcasting Company | 13 |
| Super Deformed Shorts | — | — | 3 |
| Super Duper Sumos | April 7, 2002 | YTV | 26 |
| Super Friends | September 8, 1973 | American Broadcasting Company | 109 |
| Super Friends: The Legendary Super Powers Show | September 8, 1984 | American Broadcasting Company | 8 |
| Super Giant Robot Brothers | August 4, 2022 | Netflix | — |
| Super Mario World | September 14, 1991 | NBC | 13 |
| Super Monsters | October 13, 2017 | Netflix | 22 |
| Super President | September 16, 1967 | NBC | 30 |
| Super Robot Monkey Team Hyperforce Go! | September 18, 2004 | Jetix, Freeform, Disney XD | 52 |
| Super Why! | September 3, 2007 | PBS Kids, CBC Kids | 103 |
| Super Why's Comic Book Adventures | October 5, 2026 | — | — |
| Super Wings | September 1, 2014 | Korea Educational Broadcasting System, Carousel | 424 |
| Superbook | October 9, 1981 | Christian Broadcasting Network | 52 |
| Superbook | September 1, 2011 | Christian Broadcasting Network | 52 |
| Superbuns | October 17, 2023 | Treehouse TV, Universal Kids, Peacock | — |
| Superhero Kindergarten | April 23, 2021 | — | 26 |
| Superjail! | May 13, 2007 | Adult Swim | 36 |
| Superman | September 17, 1988 | CBS | 13 |
| Superman: The Animated Series | September 6, 1996 | The WB, Kids' WB | 54 |
| SuperMansion | October 8, 2015 | — | 46 |
| Supermodels | June 14, 1999 | Antena 3 | — |
| Supernatural Academy | January 20, 2022 | Peacock | — |
| SuperNews! | August 19, 2005 | Current TV | 67 |
| Swamp Thing | October 31, 1990 | Fox Broadcasting Company, USA Network, Fox Kids | 5 |
| SWAT Kats: The Radical Squadron | September 11, 1993 | TBS | 23 |
| Sylvanian Families | September 18, 1987 | Broadcast syndication | 13 |